Medicine should not be one-size-fits-all
We're bringing advances in statistical machine learning to drug development. It's now possible to evaluate and communicate the safety and efficacy of therapies for the patient as well as the population.
Why Us?
Usability
Our platform makes models usable by non-statisticians -- models become useful when they are used by people who have to make decisions.
Algorithms
Recent advances in computational statistics allow us to tackle models previously thought too difficult due to non-linearities and the number of unknowns.
Predictive Accuracy
In-sample predictions are easy. Our models make well calibrated predictions out of sample: for a new patient, a new study arm, and even a new trial.
Interpretability
Our models are generative, transparent, explainable, and testable. In contrast to black box methods, we know what these models are doing.
Small Data
Our models work well in the small data regime, such as in Rare Diseases, where we need to take advantage of information external to the clinical trial.
Model Types
Pharmacometric Models
Using Ordinary Differential Equation (ODE) solvers we encode how the drug diffuses through different parts of the body.
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Joint Survival Models
Linking the model for the hazard with submodels for individual biomarkers. Joint models for comorbidities.
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Genomic Models
Retain proper uncertainties and produce more accurate predictions than popular tools like Lasso and PCA.
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Personalized Brain Network Models
Used in modeling the brain dynamics of epileptic seizures with stochastic differential equations.
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